Constance ''Constandina'' H. (Mehos) Giuffre, Of Wakefield, formely of Malden, December 11, 2006. Beloved wife of the late Anthony J. Giuffre. Devoted Mother of Gene Paul Giuffre & his wife Gretchen, Elaine Barriss and Mary Jennings. Loving sister of George Mehos, Chrisanthi Doulas& Her husband George and Amelia Brown& The late Nicholas Mehos. Sister in law of Barbara Mehos and the late Demetria Mehos & the late James Brown. Loving Grandmother of Jennifer Paolini& her husband Michael, Andrea Giuffre, Adam Giuffre and Matthew Giuffre. Great Grandmother of Isabella Paolini. Also survived by many nieces, nephews and relatives. In lieu of flowers donations in her memory may be made to the Children's Hospital, 300 Longwood Ave. ,Boston Ma. 02115.